Red Bull Arena | Thursday 21 July 2022 at 18:15 UK local time
| RasenBallsport Leipzig | 0 | - | 5 | Liverpool |
| Adrián San Miguel |
| Trent Alexander-Arnold |
| Andy Robertson |
| Virgil Van Dijk |
| Ibrahima Konaté |
| Thiago Alcantara |
| Naby Keita |
| Fabinho Tavares |
| Roberto Firmino |
| Mohamed Salah |
| Luis Diaz |
| Andy Robertson replaced by Kostas Tsimikas 46′ |
| Ibrahima Konaté replaced by Joël Matip 46′ |
| Naby Keita replaced by Jordan Henderson 46′ |
| Roberto Firmino replaced by Darwin Nunez 46′ |
| Luis Diaz replaced by Stefan Bajcetic 60′ |
| Adrián San Miguel replaced by Harvey Davies 61′ |
| Trent Alexander-Arnold replaced by Joe Gomez 61′ |
| Virgil Van Dijk replaced by Curtis Jones 61′ |
| Thiago Alcantara replaced by Harvey Elliott 61′ |
| Fabinho Tavares replaced by James Milner 61′ |
| Mohamed Salah replaced by Fabio Carvalho 61′ |
| Liam Hughes |
| Isaac Mabaya |
| Nathaniel Phillips |
| Sepp van den Berg |
| Tyler Morton |
Opposition
Lineup: Gulacsi (Blaswich 46'), Henrichs (Novoa 59'), Simakan (Klostermann 46'), Orban , Halstenberg (Ba 78'), Angelino, Kampl (Haidara 59'), Szoboszlai (60') (Schlager 60'), Nkunku (Forsberg 59'), Olmo (Laimer 60'), A Sorloth (Silva 33')
Unused subs: Mukiele, Nickish, Schlieck